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Ketamine Nasal Spray Shows Promise Against Tough-to-Treat Depression

A nasal spray containing a ketamine derivative appears to beat one of the standard drugs used for people with difficult-to-treat depression, a new clinical trial has found.

The trial, of nearly 700 people with treatment-resistant depression, found that esketamine nasal spray was more effective at sending patients into remission than a standard oral drug called quetiapine (Seroquel).

Could 'Float Therapy' Help Ease Anorexia?

Float therapy, where a patient is suspended in a pool of warm, salty water in a soundproof room, could help ease some aspects of anorexia nervosa, a small new study found.

"The idea is that women with anorexia have dysfunctional interoceptive abilities [sensing internal signals from your body], so they're not able to attend to and perceive their bodily experiences in the same way that he...

Nursing Homes Used COVID Meds Less Than Expected During Pandemic

While nursing home residents are at high risk for bad outcomes if they get COVID-19, use of antiviral treatments, such as monoclonal antibodies, was low through most of 2021 and 2022.

The authors of a new study, led by Brian McGarry, a health services researcher at the Un...

New Drug May Treat Rare Diseases That Make Exposure to Sunlight Painful

It sounds like the stuff of a vampire novel, but for people with a group of rare genetic disorders, exposure to sunlight can cause excruciating pain.

Now, an experimental medication is showing promise for helping them better tolerate the light of day.

In an early clinical trial, researchers tested the drug for patients with either of two related conditions: erythropoietic protoporp...

Breakthrough CAR-T Cancer Treatments Are Boosting Patients' Quality of Life

A therapy that bolsters the immune system may not only help certain cancer patients live longer, but better, a new study finds.

The treatment, called chimeric antigen receptor (CAR) T-cell therapy, is used to fight certain types of blood cancer -- including leukemia and lymphoma -- that have not responded to standard treatments.

It involves removing a patient's own immune system T-c...

Monoclonal Antibody Treatments Cut COVID Hospitalizations, Deaths by 39%

Monoclonal antibodies have been an effective tool in the battle against COVID-19, reducing the risk of hospitalization or death by 39% for people who started the treatment within two days of a positive test, a new study finds.

These treatments were even more effective for immunocompromised people, regardless of age, according to the University of Pittsburgh re...

Drug Combo Shows Promise Against Advanced Head and Neck Cancer

An experimental targeted drug could provide a fresh chance for people with recurring head and neck cancer that has grown resistant to other treatments, a new clinical trial says.

Ficlatuzumab used in combination with the already approved targeted drug cetuximab (Erbitux) significantly improved progression-free survival in relapsed head and neck cancer patients, according to results from a...

New Drug Combo Buys More Time for Advanced Endometrial Cancer Patients

Researchers have discovered that two drugs might be better than one for women who have advanced endometrial cancer.

Combining chemotherapy and immunotherapy or a monoclonal antibody at the same time helped these patients live longer without their cancer progressing, especially those who had a specific type of endometrial cancer known as a mismatch repair-deficient tumor.

"We found a...

Getting Rehab at Home After Heart Attack Can Extend Lives

After a heart attack, home rehab can literally be a lifesaver, a new study finds.

Taking part in a home-based cardiac rehabilitation program lowered the risk of dying from heart complications by 36% within four years, compared with patients who were not in a rehab program, researchers report.

"Cardiac rehabilitation programs save lives," said lead researcher

  • Steven Reinberg HealthDay Reporter
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  • March 1, 2023
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    • Types of Psychotherapy: Finding the Right Fit for Your Needs

    For anyone struggling with a mental health issue who is looking for support coping with stress or managing complicated feelings, help is available.

    It's called psychotherapy, and it might be the answer you're looking for.

    According to the American Psychiatric Association

    'Neuroprotectant' Drug Could Boost Outcomes After a Stroke

    Using a "neuroprotectant" drug alongside the standard surgical removal of a clot may slash the risk of death and disability following a stroke, a new study finds.

    The new medication, called ApTOLL, shields brain tissue from continuing damage by cooling down inflammation, the researchers said.

    A stroke occurs when blood supply to part of the brain is blocked by a clot or when a ...

    Home Drug Infusions Can Be Dangerous, But Many Home Care Staff Aren't Trained

    Intravenous (IV) lines are generally associated with medical centers -- picture a patient in a hospital bed, an IV drip-dropping needed fluids, nutrients and medicines into their arm.

    But millions now are receiving IV treatments at home, and a new study warns that not enough people are being p...

    Singing Might Aid Recovery After a Stroke

    Singing may help stroke patients regain communication skills, according to new research.

    About 40% of stroke survivors have aphasia, a difficulty to deliver or comprehend spoken or written language. That impairment is ongoing for about half of those patients a year after their stroke, potentially affecting quality of life or leading to social isolation.

    Researchers in Finland studie...

    Melanoma Patients Who Fail Standard Meds May Have Another Option

    An experimental therapy that uses the body's own immune system cells may beat a standard treatment for patients with advanced melanoma, a new clinical trial finds.

    Researchers found that the therapy doubled the amount of time melanoma patients lived without their skin cancer progressing, versus a long-used drug called ipilimumab (Yervoy).

    The approach, called tumor-infiltrating...

    Two Veterinary Meds Show Promise Against a Tough Foe: Bed Bugs

    Two common drugs that veterinarians use to kill parasites on pets could be the solution to getting rid of bed bugs.

    Both fluralaner and ivermectin, which are used to kill fleas and ticks on household pets, could also kill bed bugs. The newer, longer-lasting fluralaner showed especially strong potential.

    This

  • Cara Murez HealthDay Reporter
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  • December 1, 2022
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    • Had a Stroke? Get These Professionals on Your Rehab Team

    When someone has a stroke, many professionals come together to help the patient recover.

    The rehabilitation plan varies depending on which parts of the body were affected by the stroke and the type...

    Kidney Stones Can Be Excruciating. New Treatment Blasts Them Away, No Anesthesia Needed

    A new ultrasound treatment for kidney stones might provide pain-free relief while the patient is awake, researchers say.

    Kidney stones are often excruciatingly painful. In most cases, patients are told to just ride it out, sometimes for weeks, in the hope the stone will ...

    Thousands of U.S. Patients Got COVID Treatments Rejected as Useless by FDA

    U.S. doctors administered more than 150,000 doses of useless monoclonal antibody treatments to COVID-19 patients early this year, spending loads of cash on therapies that had been deemed of no benefit, a new study has found.

    New MS Treatment Shows Promise in Trial

    An experimental antibody therapy for multiple sclerosis can cut symptom flare-ups by half, versus a standard treatment, a new clinical trial has found.

    The drug, called ublituximab, beat a standard oral medication for

  • Amy Norton HealthDay Reporter
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  • August 25, 2022
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    • Meth Plays Big Role in Drug ODs in Rural America

    Methamphetamine is driving an epidemic of drug overdoses in rural America, a new study concludes.

    Researchers attribute the surge to meth laced with fentanyl or combined with an opioid that contains fentanyl.

    "

    Nerve Block Plus Lidocaine Clears Psoriasis in Small Study

    Spinal injections of a common anesthetic may help clear the inflammatory skin condition psoriasis, a small pilot study suggests.

    The study involved four patients with severe psoriasis, and researchers are describing it as a "proof-of-concept" -- specifically, the idea that targeting certain sens...

    U.S. Cancer Survivors Now Number 18 Million

    More than 18 million Americans have now survived cancer, a new report shows.

    The American Cancer Society (ACS) and the U.S. National Cancer Institute collaborated on the report to estimate cancer prevalence and help public health officials better serve survivors.

    "As the popula...

    New Approach Cuts Odds for Anal Cancer in People With HIV

    Treating precancerous anal growths in people with HIV slashes their risk of anal cancer by more than half, according to a new study.

    Researchers found that treating these growths - called high-grade squamous intraepithelial lesions (HSIL) - is a safe a...

    Gene Test Lets Some Colon Cancer Patients Safely Skip Chemo

    A blood test could save some colon cancer patients from getting unnecessary chemotherapy following surgery, while making sure that those who would benefit from the treatment get it, researchers report.

    The circulating tumor DNA (ctDNA) test looks for minute amounts of genetic material that are released by...

    New Treatments Battle Advanced Breast Cancers

    Two "smart bomb" drugs are offering new hope to women with aggressive breast cancers, a pair of clinical trials show.

    Both medications are antibody-drug conjugates, consisting of a chemo drug that's been wedded to an antibody that delivers the chemotherapy directly to ca...

    COVID Can 'Rebound' After Treatment With Paxlovid, CDC Says

    COVID-19 can make a comeback after an infected person has gone through a round of Paxlovid, the antiviral used to minimize a bout with the coronavirus, according to an advisory issued Tuesday by the U.S. Centers for Disease Control and Prevention.

    "Recent case reports document that some patients with normal immune response who have completed a five-day course of Paxlovid for laboratory-co...

    Cancer Patients Have Even Greater Need for COVID Boosters: Study

    Cancer patients continue to face more risk from COVID-19, even if they've been vaccinated.

    Although vaccination is effective for most people who have cancer (even though they're immunocompromised by the disease and their cancer treatments), its effectiveness wanes more rapidly in this group, by three to six months compared to the general population, new research shows.

    The U....

    It's Getting Tougher to Find Spanish-Language Mental Health Services in U.S.

    Mental health has become a hot topic during the pandemic, but some groups have been burdened by having too few services available even before the challenges of these past two years.

    A new study found that while the Hispanic population in the United States grew by almost 5% between 2014 and 2019, Spanish-language mental health services dropped by about 18% during that same time.

    "

    COVID Drug Paxlovid Might Also Fight Long COVID

    An antiviral drug used to treat high-risk COVID-19 patients may also benefit patients with long COVID, researchers say.

    Paxlovid has U.S. Food and Drug Administration emergency use authorization to treat COVID-19 patien...

    Could Asthma Treatment Raise Your Odds for Obesity?

    Adults who suffer from asthma often need to take corticosteroids to open up their airways, but the medications may have an unintended side effect: New research shows the treatment, particularly when taken in pill form, raised the risk of patients becoming obese.

    "

  • Steven Reinberg HealthDay Reporter
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  • May 2, 2022
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    • Therapies That Can Help Ease Long COVID Breathlessness, Fatigue

    Occupational therapy or low-impact exercise might be the key to relieving long-haul COVID symptoms like extreme fatigue, breathlessness and brain fog, a pair of new studies from Ireland suggest.

    The studies reflect two different - in some ways, opposite - approaches to dealing with symptoms that tend to plague

  • Dennis Thompson HealthDay Reporter
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  • May 2, 2022
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    • More DNA Errors Seen in Brain Cells of Alzheimer's Patients

    Genetic mutations build up faster in the brain cells of Alzheimer's disease patients than in other people, new research reveals.

    The discovery could point the way to new Alzheimer's treatments.

    DNA errors called

  • By Robert Preidt HealthDay Reporter
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  • April 22, 2022
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    • Mesh Plug a New Option for Treating Tricky Aneurysms

    A mesh plug normally used to treat one type of brain aneurysm is also effective when dealing with another type, a new study says.

    Aneurysms are bulges in blood vessels that can cause a life-threatening rupture. They typically occur where a blood vessel forks into two branches (bifurcates), but can also occur on the side of a blood vessel.

    The study found that a device called a Woven...

    How the 'Magic Mushroom' Drug May Tweak the Brain to Ease Depression

    Psilocybin - the active component in "magic mushrooms" - may help rewire the brains of people with depression.

    Psychedelics including psilocybin have shown promise in treating many mental health disorders in recent years, and a new study is among the first to begin to unravel precisely how they work.

    "T...

    Sitting Tai Chi Helps Stroke Survivors Recover

    Sitting tai chi provides stroke survivors with recovery benefits similar to those achieved with standard rehabilitation, a new study finds.

    Tai chi involves a series of slow movements of the han...

    More Destructive Variant of HIV Spotted in the Netherlands

    If the pandemic taught the world nothing else, it's that viruses can mutate, potentially giving rise to new and more harmful variants.

    Now, new research reveals that's exactly what has happened with HIV, the virus that causes AIDS.

    Called VB (for virulent subtype B), the "new" HIV variant actually seems to have emerged more than 30 ...

    Could the 'Love Hormone' Help Drive Sex Addiction in Men?

    Men compelled to find myriad new partners and ways to have sex may be driven by high levels of the so-called "love hormone," oxytocin, new research suggests.

    Oxytocin, which is produced by the hypothalamus and secreted by the pituitary gland, plays a key role in sexual behavior, and abnormal levels are believed...

    Exercise Might Boost Outcomes for People Battling Esophageal Cancer

    Alan Holman didn't stop exercising when told he had cancer, and he's glad of it, now that U.K. researchers say moderate exercise may improve chemotherapy outcomes in esophageal cancer patients.

    Holman, 70, was diagnosed with esophageal cancer in December 2016, shortly after retiring from his job as a facilities manager at a shopping mall in Britain. Like many patients, he underwent

    'Dr. Chimp Will See You Now'? Primates Use Medicine, Study Suggests

    Chimpanzees aren't monkeying around when they catch insects and place them on open wounds, researchers report.

    An ongoing study of about 45 chimps in Loango National Park in Gabon is the first to document via video that such "healing" behavior is occurring, according to the team from Osnabrück University in Germany and the Ozouga Chimpanzee Project. The study was published Feb. 7 in th...

    Pre-Op Treatment May Be Advance Against Deadly Liver Cancers

    When delivering a liver cancer diagnosis, Dr. Thomas Marron pulls no punches: "Liver cancer is one of the deadliest cancers," he tells patients.

    Jeffrey Foster heard a similar message loud and clear when he was first diagnosed by another doctor with hepatocellular carcinoma -- the most common type of liver cancer

    In a First, a Robot Performs Laparoscopic Surgery on Pig Without Human Help

    A robot performed challenging keyhole surgery on pigs without any human help in what could be a major step toward fully automated surgery on people.

    "Our findings show that we can automate one of the most intricate and delicate tasks in surgery: the reconnection of two ends of an intestine," said senior study author Axel Krieger. He is an assistant professor of mechanical engineering at J...

    Saline IV Drip Just as Good as Pricier Options in Hospital ICUs: Study

    Saline intravenous (IV) fluids are as effective as more costly solutions in treating intensive care patients and keeping them alive, Australian researchers report.

    "Just about every patient admitted to the intensive care unit (ICU) will receive intravenous fluids for resuscitation or as part of standard treatment," noted

  • Robert Preidt
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  • January 26, 2022
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    • Some Patients With Macular Degeneration Could Stop Monthly Eye Injections

    Injection medications can save the vision of older people with macular degeneration, but the ongoing regimen is taxing. Now a preliminary study raises the possibility that some patients can safely be "weaned off" the treatment.

    Researchers found that of just over 100 patients they treated with the eye injections, nearly one-third were able to "pause" the therapy within the first year. And...

    After Heart Attack, Cardiac Rehab Begins Road to Recovery

    Your heart is in an incredibly vulnerable state if you've suffered a heart attack or are fighting heart failure, and cardiac rehabilitation could be an important part of your recovery.

    Unfortunately, not enough older folks appear to be taking advantage of this life-saving therapy.

    Fewer than one in 10 eligible Medicare beneficiaries get recommended heart failure rehab treatments, th...

    Few Countries Do Well Caring for the Dying

    Americans don't like to dwell on dying, so maybe it isn't surprising that compared to other nations, the United States does just a middling job of providing a good death.

    The United States ranked in the middle of 81 countries rated on how well their health care systems provide end-of-life care.

    Only six countries -- the United Kingdom, Ireland, Taiwan, Australia, South Korea and Cos...

    COVID-19 Treatments: What You Need to Know

    Two years into the pandemic, coronavirus treatments like monoclonal antibodies and antiviral pills have been approved to treat COVID-19, but it's hard to keep track of which ones still work, experts say.

    For example, the monoclonal ant...

    For Transgender People, Starting Hormone Therapy in Teens Helps Mental Health

    Transgender people get greater mental health benefits if they start gender-affirming hormone treatment when they're teens instead of waiting until they're adults, a new study finds.

    "This study is particularly relevant now because many state legislatures are introducing bills that would outlaw this kind of care for

  • Robert Preidt
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  • January 14, 2022
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    • Immune-Based Drug Fights Advanced Endometrial Cancer: Study

    A drug used to treat several types of cancer is also an effective treatment for aggressive forms of endometrial cancer, the second most common cancer in women worldwide, a new clinical trial shows. The endometrium is the inner lining of the uterus.

    "These findings suggest a long-term benefit to patients," said lead researcher Dr. David O'Malley, a gynecologic oncologist at the Ohio State ...

    FDA OKs Pfizer Pill as First At-Home COVID Treatment

    The U.S. Food and Drug Administration on Wednesday approved the emergency use of Pfizer's new antiviral pill Paxlovid in people who are at high risk for severe COVID-19. It's the first approved treatment for COVID-19 meant to be taken at home.

    "Today's authorization introduces the first treatment for COVID-19 that is in the form of a pill that is taken orally -- a major step forward in t...

    NYC's Overdose Prevention Centers Already Saving Lives

    At least 59 overdoses were prevented in the first three weeks that two overdose prevention centers have been open in New York City, the city's health department said Tuesday.

    During that time, there were more than 2,000 visits to the centers that are operated by OnPoint NYC and are the first publicly recognized overdose prevention sites to open in the United States. The city first